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SQSTM1 抗体 (AA 232-356)

This anti-SQSTM1 antibody is a 小鼠 单克隆 antibody detecting SQSTM1 in WB, IHC, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN1846090
发货至: 中国

Quick Overview for SQSTM1 抗体 (AA 232-356) (ABIN1846090)

抗原

See all SQSTM1 抗体
SQSTM1 (Sequestosome 1 (SQSTM1))

适用

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宿主

  • 113
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  • 1
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小鼠

克隆类型

  • 109
  • 36
单克隆

标记

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This SQSTM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 17
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    AA 232-356

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. coli.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • 抗原

    SQSTM1 (Sequestosome 1 (SQSTM1))

    别名

    SQSTM1

    背景

    This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway.The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals.Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene.Mutations in this gene result in sporadic and familial Paget disease of bone.

    分子量

    47.7 kDa

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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